Description
A reversible inhibitor of Ser and Cys proteases with an activity spectrum comparable to leupeptin. Antipain inhibited transformation of NIH3T3 cells after transfection with an activated H-ras oncogene (Cox et al.). Vaccari et al. used antipain for evaluating the role of proteases in the process of malignant transformation of BALB/c 3T3 cells.



