Description
Experiments using sub-peptides of Aβ42 revealed that the epitope identified by the antibody A8, as described by Ying and coworkers, lies within the 1–6 region of Aβ. The antibody displays high affinity for soluble Aβ42 oligomers in the molecular weight range of 16.5–25 kDa, and detected target antigen in brain sections from senescence-accelerated SAMP 8 mice.




