Synthetic product. Potent antagonist of RANTES and macrophage inflammatory polypeptide-1α (MIP-1α). Met-RANTES inhibited RANTES- or MIP-1α-induced chemotaxis of promonocytic THP-1cells and T-cells. Although Met-RANTES antagonized RANTES and MIP-1α with similar potency in the chemotaxis response it showed a clear difference in the cytokine-induced calcium mobilization assay.
Synthetic product. Potent antagonist of RANTES and macrophage inflammatory polypeptide-1α (MIP-1α). Met-RANTES inhibited RANTES- or MIP-1α-induced chemotaxis of promonocytic THP-1cells and T-cells. Although Met-RANTES antagonized RANTES and MIP-1α with similar potency in the chemotaxis response it showed a clear difference in the cytokine-induced calcium mobilization assay.
| Pack size available | 1mg |
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